Tumor lysis syndrome with massive hyperphosphatemia and hyperuricemia

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Tumor lysis syndrome with massive hyperphosphatemia and hyperuricemia

Tumor lysis syndrome (TLS) occurs when tumor cells release their contents into the bloodstream, typically in response to chemotherapy, leading to the characteristic findings of hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and acute kidney injury. Twinkle artifacts on renal ultrasound may indicate calcium phosphate deposits in such patients.

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Rasburicase for prevention of hyperuricemia and tumor lysis syndrome.

• Hyperuricemia associated with tumor lysis syndrome is a potentially serious complication most frequently seen during chemotherapy for malignancies with large tumor burden and highly proliferative cells, such as aggressive lymphomas and leukemia.1-3 Hyperuricemia usually occurs in association with other metabolic abnormalities, including hyperphosphatemia, hyperkalemia, hypocalcemia, and azote...

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Hyperuricemia and acute renal failure secondary to spontaneous tumor lysis syndrome in myelodysplastic syndrome

Background: This is a rare instance of acute renal failure caused by hyperuricemia due to spontaneous tumor lysis syndrome and the first case of spontaneous tumor lysis syndrome reported in myelodysplastic syndrome. Case Presentation: A 53-year-old man presented with abrupt oligouria. Laboratory findings on admission suggested hyperuricemia, hyperphosphatemia, hypocalcinemia, metabolic acidosis...

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Hyperuricemia and acute kidney injury secondary to spontaneous tumor lysis syndrome in low risk myelodysplastic syndrome

BACKGROUND This is a rare instance of acute kidney injury caused by hyperuricemia due to spontaneous tumor lysis syndrome and also the first case of spontaneous tumor lysis syndrome reported in association with myelodysplastic syndrome. CASE PRESENTATION A 53-year-old man presented with abrupt oliguria. Laboratory findings on admission included hyperuricemia, hyperphosphatemia, hypocalcemia, ...

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Frequency of Tumor Lysis Syndrome in Aggressive and Slow Introduction Chemotherapy in Children with ALL

Abstract Background Tumor Lysis Syndrome (TLS) is an oncologic emergency that results from massive lysis of malignant cells. The incidence of TLS depends on the risk factors, such as baseline hyperuricemia, bulky tumor burden, elevated serum LDH, and elevated WBC. The objectives of the present study were to assess frequency of Tumor Lysis Syndrom in children with ALL in two methods of inducti...

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2017

ISSN: 2050-0904

DOI: 10.1002/ccr3.1268